Erythroblastosis Fetalis - Diagnosis

Diagnosis

The diagnosis of HDN is based on history and laboratory findings:

Blood tests done on the newborn baby

  • Biochemistry tests for jaundice
  • Peripheral blood morphology shows increased reticulocytes. Erythroblasts (also known as nucleated red blood cells) occur in moderate and severe disease.
  • Positive direct Coombs test (might be negative after fetal interuterine blood transfusion)

Blood tests done on the mother

  • Positive indirect Coombs test

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