Principle
The Etest is basically an agar diffusion method.
The Etest utilises a rectangular strip that has been impregnated with the drug to be studied. A lawn of bacteria is spread and grown on an agar plate, and the Etest strip is laid on top; the drug diffuses out into the agar, producing an exponential gradient of the drug to be tested. There is an exponential scale printed on the strip. After 24 hours of incubation, an elliptical zone of inhibition is produced and the point at which the ellipse meets the strip gives a reading for the minimum inhibitory concentration (MIC) of the drug.
Read more about this topic: Epsilometer Test
Famous quotes containing the word principle:
“From the age of fifteen, dogma has been the fundamental principle of my religion: I know no other religion; I cannot enter into the idea of any other sort of religion; religion, as a mere sentiment, is to me a dream and a mockery.”
—Cardinal John Henry Newman (18011890)
“There is no teaching until the pupil is brought into the same state or principle in which you are; a transfusion takes place; he is you, and you are he; then is a teaching; and by no unfriendly chance or bad company can he ever lose the benefit.”
—Ralph Waldo Emerson (18031882)
“I ... observed the great beauty of American government to be, that the simple machines of representation, carried through all its parts, gives facility for a being moulded at will to fit with the knowledge of the age; that thus, although it should be imperfect in any or all of its parts, it bears within it a perfect principle the principle of improvement.
”
—Frances Wright (17951852)