Epileptogenesis

Epileptogenesis is a process by which a normal brain develops epilepsy, a chronic condition in which seizures occur. The process, which is gradual, occurs in symptomatic epilepsy, in which seizures are caused by an identifiable lesion in the brain. It results from acute brain insults such as traumatic brain injury (physical trauma to the brain), stroke, or infection. Epileptogenesis is a series of events that occur between the event that causes epilepsy and the first spontaneous seizure. In epileptogenesis, an array of events occur on molecular and cellular levels that cause neurons to fire in a disordered manner, resulting in seizures.