Epica may refer to:
- Epica (band), a Dutch symphonic metal band
- Epica (album), an album by the power metal band Kamelot
- The European Project for Ice Coring in Antarctica (EPICA)
- The Epica Awards (International Advertising Awards)
- Epica (RAID series), a series of storage arrays developed by Proware Technology Corporation
- Daewoo Tosca, also known as Chevrolet Epica or Holden Epica
- Daewoo Magnus, also known as Chevrolet Epica
- Banksia epica, a South Australian native bush