In physics and biochemistry, an energy landscape is a mapping of all possible conformations of a molecular entity, or the spatial positions of interacting molecules in a system, and their corresponding energy levels, typically Gibbs free energy, on a two- or three-dimensional Cartesian coordinate system.
The term is useful when examining protein folding; while a protein can theoretically exist in a nearly infinite number of conformations along its energy landscape, in reality proteins fold (or "relax") into secondary and tertiary structures that possess the lowest possible free energy. The key concept in the energy landscape approach to protein folding is the folding funnel hypothesis.
In glassing models, the local minima of an energy landscape correspond to metastable low temperature states of a thermodynamic system.
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Famous quotes containing the words energy and/or landscape:
“There are no accidents, only nature throwing her weight around. Even the bomb merely releases energy that nature has put there. Nuclear war would be just a spark in the grandeur of space. Nor can radiation “alter” nature: she will absorb it all. After the bomb, nature will pick up the cards we have spilled, shuffle them, and begin her game again.”
—Camille Paglia (b. 1947)
“Every landscape which is dreary enough has a certain beauty to my eyes, and in this instance its permanent qualities were enhanced by the weather. Everything told of the sea, even when we did not see its waste or hear its roar.”
—Henry David Thoreau (1817–1862)