Endoplasmic-reticulum-associated protein degradation (ERAD) designates a cellular pathway which targets misfolded proteins of the endoplasmic reticulum for ubiquitination and subsequent degradation by a protein-degrading complex, called the proteasome.
Read more about Endoplasmic-reticulum-associated Protein Degradation: ERAD Ubiquitination Machinery, Checkpoints, Diseases Associated With ERAD-malfunctioning, ERAD and HIV, Questions
Famous quotes containing the words protein and/or degradation:
“Firm-style bean curd insoles cushion feet, absorb perspiration and provide more protein than meat or fish innersoles of twice the weight. Tofu compresses with use, becoming more pungent and flavorful. May be removed when not in use to dry or marinate. Innersoles are ready to eat after 1,200 miles of wear. Each pair provides adult protein requirement for 2 meals. Insoles are sized large to allow for snacks. Recipe booklet included.”
—Alfred Gingold, U.S. humorist. Items From Our Catalogue, “Tofu Innersoles,” Avon Books (1982)
“History is nothing but a procession of false Absolutes, a series of temples raised to pretexts, a degradation of the mind before the Improbable.”
—E.M. Cioran (b. 1911)