Endocardial Fibroelastosis - Characteristics

Characteristics

EFE is characterized by a thickening of the inmost lining of the heart chambers (the endocardium) due to an increase in the amount of supporting connective tissue and elastic fibers. It is an uncommon cause of unexplained heart failure in infants and children, and is one component of HEC syndrome Fibroelastosis is strongly seen as a primary cause of restricted cardiomyopathy seen in children, along with cardiac amyloidosis, which is more commonly seen in progressive multiple myeloma patients and the elderly.

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