EIS may refer to:
- Terrance B. Lettsome International Airport, an airport in the British Virgin Islands which has IATA airport code EIS
- Eastern Independent Schools of Melbourne, a group of schools in Australia
- Educational Institute of Scotland, a Scottish teachers' trade union
- Ekamai International School, an International school in Bangkok, Thailand
- Electrical insulation system, see electrical insulation
- Electrochemical Impedance Spectroscopy
- Electro Interstitial Scanner, E.I.S in medicine
- Electrolyte-Insulator-Semiconductor, a sensor
- Electronic Instrument System, a component of the glass cockpit in an MD-11 Aircraft
- Embryo-carrying Interstellar Starship, a concept in space colonization
- Engineering Installation Squadron, a US Air Force squadron
- English Institute of Sport, a network of sports related services
- Enhanced Imaging System, a US satellite project
- Enterprise Information System, an organization-wide information system
- Enterprise Investment Scheme, a UK tax relief
- Entry into Service, Abbreviation
- Environmental impact statement, an assessment of the likely impact a project may have, required for projects receiving federal funding in the United States
- Epidemic Intelligence Service, a US training program
- Epigenetic inheritance system, a concept in genetics
- Equal Interval System, a system of music composition developed by Spud Murphy
- Erasure Information Service, the current website (and former fanclub) for the pop band Erasure
- Escuela Internacional Sampedrana, a school in Honduras
- Esquadron d'Intervention Spécial, the former name of the Belgian police's counter-terrorism unit
- European Ice Services
- European Integration Studio, an Electronic Arts studio
- European Invertebrate Survey, a map grid-system based on 50x50 km squares
- Executive Information System, a form of decision support system
- Expressive Intelligence Studio, a game design research group at University of California, Santa Cruz
- Extreme-ultraviolet Imaging Spectrometer, a scientific instrument on board the Hinode satellite studying the Sun