Edwin Joseph Cohn - Physical Chemistry of Proteins

Physical Chemistry of Proteins

Cohn is also well-remembered for his studies of the physical chemistry of proteins, particularly his general "salting out" equation for protein solubility (1925)

$\log K_{p} = - \alpha_{S} + \beta_{S}$

where is the protein solubility constant and and are constants characteristic of the particular ion S whose concentration (or, more correctly, activity) is . This equation is identical to the Setschenow solubility equation (Setschenow, 1889)

Cohn was a long-time collaborator and friend of another important physical chemist, George Scatchard.

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