Ecotoxicology - Ecotoxicity Testing

Ecotoxicity Testing

- Acute and chronic toxicity tests are performed for terrestrial organisms including avian, mammalian, nontarget arthoprods, and earthworms.

- The Organization for Economic Cooperation and Development (OECD) test guideline has developed specific tests to test toxicity level in organisms.

- LC50 is the acute toxicity test which tests for the concentrate of tissue at which it is lethal to 50% within 96 hours. The test may start with eggs, embryos, or juveniles and last from 7 to 200 days.

- EC50 is the effective concentration at 50% which is the concentration which causes adverse effects in 50% of the test organisms.

- Endocrine Disruptor Screening Program (EDSP0

 Tier 1 screening battery

- Endangered species assessments.

- Persistent, Bioaccumulative, and Inherently Toxic (PBiT) assessments using the Quantitative Structure-Activity Relationships (QSARs) to categorize regulated substances. - Bioaccumulation in fish using the Bioconcentration Factor (BCF) methods.

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