Eastport may refer to:
- Eastport, California, United States
- Eastport, Maine, United States
- Eastport, New York, United States
- Eastport, Newfoundland and Labrador, Canada
- Maritime Republic of Eastport, a tongue-in-cheek secessionist movement in Annapolis, Maryland
- USS Eastport (1862), a steamer
- EastPort UK, a trading name for the Great Yarmouth Port Company