Effects
Cannabis has psychoactive and physiological effects when consumed. The minimum amount of THC required to have a perceptible psychoactive effect is about 10 micrograms per kilogram of body weight. Aside from a subjective change in perception and, most notably, mood, the most common short-term physical and neurological effects include increased heart rate, increased appetite and consumption of food, lowered blood pressure, impairment of short-term and working memory, psychomotor coordination, and concentration. Long-term effects are less clear.
Deaths attributed directly to cannabis usage are infrequent but have been documented. Recorded fatalities resulting from cannabis overdose in animals are generally only after intravenous injection of hashish oil.
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—Henry David Thoreau (1817–1862)