In substance dependence and recreational drug use, drug injection is a method of introducing a drug into the body with a hollow needle and a syringe which is pierced through the skin into the body (usually intravenous, but also intramuscular or subcutaneous). This act is often colloquially referred to as "slamming", "shooting ", "banging", "pinning", or "jacking-up", often depending on the specific drug subculture in which the term is used (i.e. heroin, cocaine, methamphetamine).
Although there are various methods of taking drugs, injection is favoured by some users as the full effects of the drug are experienced very quickly, typically in five to ten seconds. It also bypasses first-pass metabolism in the liver, resulting in a higher bioavailability for many drugs than oral ingestion would (so users get a stronger effect from the same amount of the drug). This shorter, more intense high can lead to a dependency, both physical and psychological, developing more quickly than with other methods of taking drugs. As of 2004 there were 13.2 million people worldwide who used injection drugs of which 22% are from developed countries.
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... the subsequent decade, although the first well-known attempt to inject drugs into the body was a 1667 attempt to inject a solution of opium into a dog ... morphine appetite" or "codeine appetite") was due to the drug's action on the digestive system—just like any hunger or thirst—caused doctors to opt to inject morphine rather than administer it ... is often given to Dr Pravaz' wife although habituation through orally ingesting the drug was known before this time, including Sertürner and associates, followers, and his wife and dog ...
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