Draize Test - Differences Between The Rabbit Eye and The Human Eyes

Differences Between The Rabbit Eye and The Human Eyes

Kirk Wilhelmus, professor in the Department of Ophthalmology at Baylor College of Medicine, conducted a comprehensive review of the Draize eye test in 2001. He also reported that differences in anatomy and biochemistry between the rabbit and human eye indicate that testing substances on rabbits might not predict the effects on humans. However, he noted "that eyes of rabbits are generally more susceptible to irritating substances than the eyes of humans" making them a conservative model of the human eye. Wilhelmus concluded "The Draize eye test ... has assuredly prevented harm" to humans, but predicts it will be "supplanted as in vitro and clinical alternatives emerge for assessing irritancy of the ocular surface"

Read more about this topic:  Draize Test

Famous quotes containing the words differences between, differences, rabbit, eye, human and/or eyes:

    The differences between revolution in art and revolution in politics are enormous.... Revolution in art lies not in the will to destroy but in the revelation of what has already been destroyed. Art kills only the dead.
    Harold Rosenberg (1906–1978)

    When was it that the particles became
    The whole man, that tempers and beliefs became
    Temper and belief and that differences lost
    Difference and were one? It had to be
    In the presence of a solitude of the self....
    Wallace Stevens (1879–1955)

    America is no place for an artist: to be an artist is to be a moral leper, an economic misfit, a social liability. A corn-fed hog enjoys a better life than a creative writer, painter, or musician. To be a rabbit is better still.
    Henry Miller (1891–1980)

    Therefore I have uttered what I did not understand, things too wonderful for me, which I did not know. ... I had heard of you by the hearing of the ear, but now my eye sees you; therefore I despise myself, and repent in dust and ashes.”
    Bible: Hebrew, Job 42:3-6.

    Job to God.

    In philosophical inquiry, the human spirit, imitating the movement of the stars, must follow a curve which brings it back to its point of departure. To conclude is to close a circle.
    Charles Baudelaire (1821–1867)

    You can’t build life the way you put blocks together, Toddy.... Did Knox teach you what makes the blood flow? Did he tell you how thoughts come and how they go, and why things are remembered and forgot?... What makes a thought start?... You don’t know and you’ll never know or understand.... Look, look at yourself. Could you be a doctor, a healing man, with the things those eyes have seen? There’s a lot of knowledge in those eyes, but no understanding.
    Philip MacDonald, and Robert Wise. Gray (Boris Karloff)