Side Effects
- Dysphoria
- Parkinsonism – due to effects on the nigrostriatal pathway
- Hyperprolactinaemia – due to effects on the tuberoinfundibular pathway
- Tardive dyskinesia (long term use)
- galactorrhea - due to removal of dopamine-mediated inhibition of prolactin release from lactotroph cells in the anterior pituitary
- sexual dysfunction and impotence - due to blockage of the pleasure center (dopaminergic pathways)
- Sedation
- Irritability
- Narcolepsy
- Symptoms similar to ADHD
- Increased risk of severe depression
- Anxiety disorders (such as Social Phobia)
- Increased appetite
- Increased risk of obesity
- Paranoia
- Aggression
- Psychomotor agitation (e.g. pacing)
- Increased risk of Type 2 Diabetes mellitus
- Akathisia
- Extrapyramidal symptoms
- Clinical depression
Other side effects may include menstrual dysfunction, low libido, and impotence.
Read more about this topic: Dopamine Antagonist
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