Mechanics of Docking
To perform a docking screen, the first requirement is a structure of the protein of interest. Usually the structure has been determined using a biophysical technique such as x-ray crystallography, or less often, NMR spectroscopy. This protein structure and a database of potential ligands serve as inputs to a docking program. The success of a docking program depends on two components: the search algorithm and the scoring function.
Read more about this topic: Docking (molecular)
Famous quotes containing the words mechanics of and/or mechanics:
“It is only the impossible that is possible for God. He has given over the possible to the mechanics of matter and the autonomy of his creatures.”
—Simone Weil (1909–1943)
“It is only the impossible that is possible for God. He has given over the possible to the mechanics of matter and the autonomy of his creatures.”
—Simone Weil (1909–1943)