DNR may refer to:
- Do not resuscitate, a medical instruction
- "DNR" (House episode), an episode from the American television program House
- The final episode of Becker (TV series), an American sitcom
- "D.N.R. (Do Not Resuscitate)", a song by the American heavy metal band Testament, from their 1999 album The Gathering
- Daunorubicin, a chemotherapy drug
- Department of Natural Resources (disambiguation), a name of various government entities
- Dialed Number Recorder, another name for a pen register which is used to record the phone numbers dialed on a phone line.
- Dinard - Pleurtuit - Saint-Malo Airport in France (IATA code: DNR)
- Direct normal radiation, a measure of sunlight intensity, not counting sunlight scattered by atmosphere.
- Dynamic Noise Reduction, an audio noise reduction system
- Dolby noise reduction system, an audio noise reduction system often confused with DNR
- Digital noise reduction, digital processes used to improve digital copies, often from analog sources
- Radio DNR Luxembourg, a Luxembourg radio station
- Daily News Record, a closed American fashion trade journal
- DNR (Dreams Not Reality) is an Italian Eurovisual band.