Clinical Significance
Because of the epigenetic effects of the DNMT family, some DNMT inhibitors are under investigation for treatment of some cancers:
- Vidaza (5-azacitidine) in a phase II trial for AML
- Dacogen (decitabine) in phase III trials for AML and CML
Read more about this topic: DMNT
Famous quotes containing the word significance:
“The hysterical find too much significance in things. The depressed find too little.”
—Mason Cooley (b. 1927)