DLC may refer to:
- Dalian Zhoushuizi International Airport, which has the IATA code DLC, a military and public airport in Ganjingzi District, Dalian, China
- Dead Letter Circus, an alternative rock band from Brisbane, Queensland, Australia
- Delocalized coordinates, a variant of internal coordinates in computational chemistry
- Democratic Leadership Council, an American nonprofit political corporation that argues for a centrist viewpoint
- Development life cycle, the process of product development
- Developmental Learning Centre, a common name for special schools or similar institutions
- Diamond-like carbon, seven different forms of amorphous carbon materials that display some of the typical properties of diamond
- Digital Liberty Coalition, a non-profit anti-censorship organization in Australia
- Domestic and light commercial, a type of insurance policy
- Driver License Compact, an interstate agreement within the United States
- Dual-listed company, an arrangement in which two corporations function as a single operating business but retain separate legal identities and stock exchange listings
- Dubai Logistics City, a multi-mode logistics platform in Dubai World Central, an urban land development in the south-west of Dubai, United Arab Emirates
- Dioxins and dioxin-like compounds, by-products of various industrial processes and the burning of waste in rural areas where proper disposal services are expensive or non-existent
- David Lewis Company, a financial consulting firm executing work in FP&A, Financial Reporting & Accounting and Financial Systems for its Fortune 1000 clients.
- Computing and technology
- Data Link Control, a concept in the OSI network protocol
- Desktop Linux Consortium, a nonprofit organization dedicated to the Linux operating system
- Digital loop carrier, a concept in electronic communications
- Discrete logarithm cryptography, a category of cryptography that includes finite field cryptography and elliptic curve cryptography
- Downloadable content, digital media available for download on the Internet, used to refer to content created for video games that is released separately from the game