History
The first global burden of disease (GBD) study (conducted in 1990) quantified the health effects of more than 100 diseases and injuries for eight regions of the world, giving estimates of morbidity and mortality by age, sex, and region. It also introduced the DALY as a new metric to quantify the burden of diseases, injuries, and risk factors.
Murray and Lopez used DALYs in their extensive study on the global burden of disease study to introduce morbidity into the predominantly mortality-based health discussions. WHO then endorsed the DALY approach. In 2000–2002 the 1990 GBD study was updated to include a more extensive analysis using an analytic framework known as comparative risk factor assessment.
Read more about this topic: Disease Burden
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—David Hume (1711–1776)