Dichloroacetic Acid - Side Effects

Side Effects

Reports in the lay press after the 2007 University of Alberta announcement claim that dichloroacetate "has actually been used safely in humans for decades", DCA is generally well tolerated, even in children. Short-term, infused, bolus doses of DCA at 50 mg/kg/day have been well tolerated.

At sustained, higher doses(generally 25 mg/kg/day taken orally, or greater), there is increased risk of several reversible toxicities, especially peripheral neuropathy, neurotoxicity, and gait disturbance.

Studies have also shown that it can be carcinogenic in male B6C3F1 mice at high doses.

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