DEU may refer to:
- Deutsche Eislauf-Union, the figure skating governing body in Germany
- Distinct Environmental Uniform, the current uniform of the Canadian Forces, adopted in the late 1980s
- Doom Editing Utility, a software utility for the computer game Doom
- The ISO 3166-1 alpha-3 country code for Germany
- Drug Enforcement Unit, a specialised police unit
- Dokuz Eylül University, a state university located in Izmir, Turkey