Dermatitis Herpetiformis

Dermatitis herpetiformis (DH), or Duhring's disease, is a chronic blistering skin condition, characterised by blisters filled with a watery fluid. Despite its name, DH is not related to or caused by herpes virus: the name means that it is a skin inflammation having an appearance similar to herpes.

DH was first described by Dr. Louis Duhring in 1884. A connection between DH and gluten intolerance (coeliac disease) was recognised in 1967, although the exact causal mechanism is not known.

The age of onset is usually about 15-40, but DH can also affect children and the elderly. Men and women are equally affected. Estimates of DH prevalence vary from 1 in 400 to 1 in 10000.

Read more about Dermatitis Herpetiformis:  Symptoms, Diagnosis, Treatment, Pathology, Complications, Notable Cases

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HLA A1-B8-DR3-DQ2 - Importance To Medicine - In Coeliac Disease & Dermatitis Herpetiformis
... B8 was identified for coeliac disease in 1973 and dermatitis herpetiformis in 1976 ... risk factors on the B8DQ2 haplotype that increase risk of dermatitis herpetiformis in coeliac disease ...
Gluten-sensitive Enteropathy Associated Conditions - Dermatitis - Dermatitis Herpetiformis
... Triticeae glutens are the primary cause of dermatitis herpetiformis(DH) ... Epidermal transglutaminase (eTG) is related to tTG and is the autoantigen of DH ...