DeBrosse, de Brosse, de La Brosse, or de la Broce is a surname and may refer to:
- Pierre de la Broce, French councilor to Phillip III
- Jacques de la Brosse, French soldier and diplomat, cupbearer to Francis I
- Jean de Brosse, French councillor and chamberlain to the King of France
- Jean IV de Brosse
- Anne de Pisseleu d'Heilly
- Salomon de Brosse, French architect
- Guy de La Brosse, French botanist, doctor, and pharmacist
- Charles de Brosses, French writer
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