DCU may mean:
- D.C. United, a Washington, D.C. soccer club
- DC Universe, the shared universe of most DC Comics publications
- Dublin City University
- DCU GAA, a Gaelic games club in Dublin City University
- Digital Federal Credit Union, a credit union based Marlborough, Massachusetts, USA
- DCU Center, an indoor arena in Worcester, Massachusetts, USA
- Delphi Compiled Unit, an object file for the Delphi programming language
- Desert Camouflage Uniform, a uniform of the U.S. Army
- Pryor Field Regional Airport, an airport Decatur, Alabama, USA with the IATA code DCU