DCLRE1A

Identifiers Symbols DCLRE1A; PSO2; SNM1; SNM1A External IDs OMIM: 609682 MGI: 1930042 HomoloGene: 8920 GeneCards: DCLRE1A Gene

Gene Ontology
Molecular function	• hydrolase activity
Cellular component	• nucleus • nucleolus
Biological process	• nucleotide-excision repair • mitosis • cell division
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9937 55947 Ensembl ENSG00000198924 ENSMUSG00000025077 UniProt Q6PJP8 Q9JIC3 RefSeq (mRNA) NM_001271816 NM_018831 RefSeq (protein) NP_001258745 NP_061301 Location (UCSC) Chr 10:
115.59 – 115.61 Mb Chr 19:
56.53 – 56.55 Mb PubMed search

DNA cross-link repair 1A protein is a protein that in humans is encoded by the DCLRE1A gene.

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000).