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- David Mitchell (builder) (1829–1916), Scottish-Australian builder
- David Mitchell (lawyer), Australian Presbyterian minister
- David Mitchell (murderer) (1972–2000), Bahamian murderer executed for his crimes
- David Mitchell (Royal Navy officer) (c. 1642–1710), Scottish admiral
- David B. Mitchell (police chief) (born 1950), American police chief from Maryland and Delaware
- David J. Mitchell, Canadian historian
- David Scott Mitchell (1836–1907), Australian founder of the Mitchell library, Sydney
- David William Mitchell (1813–1859), English zoologist and illustrator
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