Administration
Dapsone is administered orally as a 100 mg tablet or alternatively as 25 mg tablets.
To deal with dapsone-resistant leprosy cases, multidrug therapy was introduced by WHO in 1981; dapsone is administered along with rifampin and clofazimine or other antileprotic drugs.
Dapsone is administered transdermally (via the skin) as a gel 5% topical acne medication and available in 3-, 30-, and 60-gram tubes. In normal use, 0.5 grams should be administered to the face per application twice a day.
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