Immune System Cytotoxicity
Antibody-dependent cell-mediated cytotoxicity (ADCC) describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an antibody. Lymphocyte-mediated cytotoxicity, on the other hand, does not have to be mediated by antibodies; nor does complement-dependent cytotoxicity (CDC), which is mediated by the complement system.
Three groups of cytotoxic lymphocytes are distinguished:
- Cytotoxic T cells
- Natural killer cells
- Natural killer T cells
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