P450s in Biotechnology
The remarkable reactivity and substrate promiscuity of P450s have long attracted the attention of chemists. Recent progress towards realizing the potential of using P450s towards difficult oxidations have included: (i) eliminating the need for natural co-factors by replacing them with inexpensive peroxide containing molecules, (ii) exploring the compatibility of p450s with organic solvents, and (iii) the use of small, non-chiral auxiliaries to predictably direct P450 oxidation.
Read more about this topic: Cytochrome P450