Cyclin B1

Cyclin B1

Identifiers Symbols CCNB1; CCNB External IDs OMIM: 123836 HomoloGene: 68982 ChEMBL: 2412 GeneCards: CCNB1 Gene

Gene Ontology
Molecular function	• patched binding • protein binding • protein kinase binding • histone kinase activity
Cellular component	• spindle pole • condensed nuclear chromosome outer kinetochore • nucleus • nucleoplasm • cytoplasm • centrosome • cytosol
Biological process	• cell cycle checkpoint • regulation of cyclin-dependent protein kinase activity • G1/S transition of mitotic cell cycle • G2/M transition of mitotic cell cycle • mitotic prometaphase • mitotic cell cycle • oocyte maturation • in utero embryonic development • negative regulation of protein phosphorylation • protein complex assembly • mitotic metaphase plate congression • spermatogenesis • response to mechanical stimulus • negative regulation of gene expression • anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process • positive regulation of mRNA 3'-end processing • positive regulation of histone phosphorylation • tissue regeneration • response to drug • mitotic spindle stabilization • positive regulation of mitotic cell cycle • response to DDT • digestive tract development • cell division • positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle • regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle • positive regulation of attachment of spindle microtubules to kinetochore • ventricular cardiac muscle cell development • positive regulation of cardiac muscle cell proliferation • regulation of chromosome condensation • mitotic cell cycle spindle checkpoint • cellular response to iron(III) ion • cellular response to fatty acid • cellular response to organic cyclic compound • cellular response to hypoxia
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 891 n/a Ensembl ENSG00000134057 n/a UniProt P14635 n/a RefSeq (mRNA) NM_031966 n/a RefSeq (protein) NP_114172 n/a Location (UCSC) Chr 5:
68.46 – 68.47 Mb n/a PubMed search n/a

G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene.