CVM may refer to:
- Christian Vision for Men a UK registered Christian charity
- Center for Veterinary Medicine
- Climate Vulnerability Monitor
- Cervical Vertebral Malformation, a form of Wobbler's Syndrome in horses
- C virtual machine, a Java virtual machine distributed by Sun Microsystems and used on mobile devices such as the Amazon Kindle
- General Pedro J. Méndez International Airport in Ciudad Victoria, Mexico (IATA Code: CVM)
- Cégep du Vieux Montréal, a Cegep in the city of Montreal, Canada
- Comissão de Valores Mobiliários, the Securities and Exchange Commission of Brazil
- Contingent valuation method, for estimation of economic values for non-market resources that are not usually associated with market price
- Complex vertebral malformation, a genetic disease found in Holstein cattle
- Cooperation and Verification Mechanism for new member states of the European Union
- California Variegated Mutant, a rare sub-type of the Romeldale sheep breed known for its unusual color