CTDP1

CTDP1

Identifiers Symbols CTDP1; CCFDN; FCP1 External IDs OMIM: 604927 MGI: 1926953 HomoloGene: 31254 GeneCards: CTDP1 Gene EC number 3.1.3.16

Gene Ontology
Molecular function	• DNA-directed RNA polymerase activity • CTD phosphatase activity
Cellular component	• spindle pole • nucleus • nucleoplasm • nucleolus • cytoplasm • centrosome • spindle • actin cytoskeleton • midbody • spindle midzone
Biological process	• transcription from RNA polymerase II promoter • transcription elongation from RNA polymerase II promoter • protein dephosphorylation • mitosis • exit from mitosis • gene expression • viral reproduction • positive regulation of viral transcription • cell division
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9150 67655 Ensembl ENSG00000060069 ENSMUSG00000033323 UniProt Q9Y5B0 Q7TSG2 RefSeq (mRNA) NM_001202504 NM_026295 RefSeq (protein) NP_001189433 NP_080571 Location (UCSC) Chr 18:
77.44 – 77.51 Mb Chr 18:
80.41 – 80.47 Mb PubMed search

RNA polymerase II subunit A C-terminal domain phosphatase is an enzyme that in humans is encoded by the CTDP1 gene.

This gene encodes a protein which interacts with the carboxy-terminus of transcription initiation factor TFIIF, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. The protein may also represent a component of an RNA polymerase II holoenzyme complex. Alternative splicing of this gene results in two transcript variants encoding 2 different isoforms.