CSCS can stand for
- Canadian Sport Compact Series
- Center for the Study of Complex Systems at the University of Michigan
- Center for Surface Combat Systems
- Certified Strength and Conditioning Specialist
- Colorado Springs Christian School
- Coral Springs Charter School
- Construction Skills Certification Scheme
- Contingency Shuttle Crew Support
- Swiss National Supercomputing Centre
- University of Maryland University College
- pointed (CSCS) gene in cats
- Criminal sale of a controlled substance