Causes
- Deposition of crystals in joints
- Calcium-pyrophosphate dihydrate crystal formation:
- Increased production of inorganic pyrophosphate
- Decreased levels of pyrophosphatase in cartilage
- Decreased levels of cartilage glycosaminoglycans
- Hyperparathyroidism
- Hemochromatosis
- Hypophosphatasia
- Hypomagnesemia
- Hydroxyapatite deposition:
- Tissue damage
- Hyperparathyroidism
- Hypercalcemia
- Hyperphosphatemia
- Calcium Oxalate deposition:
- Enhanced production of oxalic acid due to enzyme defect
- Poor excretion of oxalic acid in renal failure
- Excessive ascorbic acid intake in renal failure
Read more about this topic: Crystal Arthropathy