Glass Transition Temperature
Some cryoprotectants function by lowering the glass transition temperature of a solution or of a material. In this way, the cryoprotectant prevents actual freezing, and the solution maintains some flexibility in a glassy phase. Many cryoprotectants also function by forming hydrogen bonds with biological molecules as water molecules are displaced. Hydrogen bonding in aqueous solutions is important for proper protein and DNA function. Thus, as the cryoprotectant replaces the water molecules, the biological material retains its native physiological structure and function, although they are no longer immersed in an aqueous environment. This preservation strategy is most often utilized in anhydrobiosis.
Read more about this topic: Cryoprotectant
Famous quotes containing the words glass, transition and/or temperature:
“Heaven has a Sea of Glass on which angels go sliding every afternoon. There are many golden streets, but the principal thoroughfares are Amen Street and Hallelujah Avenue, which intersect in front of the Throne. These streets play tunes when walked on, and all shoes have songs in them.”
—For the State of Florida, U.S. public relief program (1935-1943)
“Some of the taverns on this road, which were particularly dirty, were plainly in a transition state from the camp to the house.”
—Henry David Thoreau (1817–1862)
“The siren south is well enough, but New York, at the beginning of March, is a hoyden we would not care to miss—a drafty wench, her temperature up and down, full of bold promises and dust in the eye.”
—E.B. (Elwyn Brooks)