CRYM

CRYM

Identifiers Symbols CRYM; DFNA40; THBP External IDs OMIM: 123740 MGI: 102675 HomoloGene: 1424 GeneCards: CRYM Gene EC number 1.5.1.25

Gene Ontology
Molecular function	• transcription corepressor activity • protein homodimerization activity • thiomorpholine-carboxylate dehydrogenase activity • NADP binding • thyroid hormone binding
Cellular component	• nucleus • nucleolus • cytoplasm • mitochondrion • plasma membrane
Biological process	• negative regulation of transcription from RNA polymerase II promoter • sensory perception of sound • thyroid hormone metabolic process • thyroid hormone transport
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 1428 12971 Ensembl ENSG00000103316 ENSMUSG00000030905 UniProt Q14894 O54983 RefSeq (mRNA) NM_001014444 NM_016669 RefSeq (protein) NP_001014444 NP_057878 Location (UCSC) Chr 16:
21.25 – 21.31 Mb Chr 7:
120.19 – 120.2 Mb PubMed search

Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.