Crease may refer to:
- A Line (geometry) or mark made by folding or doubling any pliable substance
- Crease (band), American hard rock band that formed in Ft. Lauderdale, Florida in 1994
- Crease (cricket), area demarcated by white lines painted or chalked on the field of play
- Crease (hockey), volume of space in an ice rink directly in front of the goalie net as indicated by painted red lines on the rink surface
- Crease pattern, origami diagram type that consists of all or most of the creases in the final model
- Crease Range, mountain range in northernwestern British Columbia, Canada
- Skin crease, areas of skin where it folds
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