Crean is an Irish surname anglicised from the Gaelic Ó Croidheáin meaning ‘descendent of Croidheán’, and may refer to:
- David Crean, Australian politician
- Frank Crean (1916-2008), Australian politician
- Simon Crean (born 1949), Australian politician
- Thomas Joseph Crean (1873-1923), Irish soldier
- Tom Crean (1877-1938), Irish explorer of the Antarctic
- Tom Crean (basketball coach) (born 1966), American college basketball coach