Analogous Conditions in Other Animals
The MATP gene is highly conserved, especially among mammals. The human MATP gene is 82% identical to the mouse MATP gene, 79% identical to the rat MATP gene, 35% to the zebrafish version, and 30% identical to the fruitfly MATP gene. The gene is best known in humans as being the location of a mutation that results in human type IV oculocutaneous albinism (OCA4). Type IV oculocutaneous albinism, like other types of human albinism, results in hypopigmentation of the skin and eyes, with increased rates of skin cancer and reduced visual acuity. None of these effects are associated with the equine cream gene. Other human MATP polymorphisms result in normal pigment variations, specifically fair skin, light eyes, and light hair in Caucasian populations.
A polymorphism on the mouse MATP gene is known to be the cause of the underwhite coat color phenotype. The phenotype was first identified in the 1960s, and since then has been mapped successfully. Affected individuals have a reduction in eye and coat pigmentation, and irregularly shaped melanosomes.
Read more about this topic: Cream Gene, Inheritance and Expression
Famous quotes containing the words analogous, conditions and/or animals:
“The triumphs of peace have been in some proximity to war. Whilst the hand was still familiar with the sword-hilt, whilst the habits of the camp were still visible in the port and complexion of the gentleman, his intellectual power culminated; the compression and tension of these stern conditions is a training for the finest and softest arts, and can rarely be compensated in tranquil times, except by some analogous vigor drawn from occupations as hardy as war.”
—Ralph Waldo Emerson (1803–1882)
“Armies, for the most part, are made up of men drawn from simple and peaceful lives. In time of war they suddenly find themselves living under conditions of violence, requiring new rules of conduct that are in direct contrast to the conditions they lived under as civilians. They learn to accept this to perform their duties as fighting men.”
—Gil Doud, U.S. screenwriter, and Jesse Hibbs. Walter Bedell Smith (Himself)
“The vast results obtained by Science are won by no mystical faculties, by no mental processes other than those which are practiced by every one of us, in the humblest and meanest affairs of life. A detective policeman discovers a burglar from the marks made by his shoe, by a mental process identical with that by which Cuvier restored the extinct animals of Montmartre from fragments of their bones.”
—Thomas Henry Huxley (1825–95)