CPN may stand for:
- Called party number
- Calpine Corporation, New York Stock Exchange symbol CPN
- Canadian Perinatal Network
- Carnivorous Plant Newsletter
- Carpinteria (Amtrak station), California, Amtrak station code CPN
- Caspian Airlines (Iran), ICAO airline designator CPN
- Central Park North, 110th Street along Central Park in New York City
- Central Parenteral Nutrition
- Central Pattana, Stock Exchange of Thailand symbol CPN
- Certified Pediatric Nurse, certification by the Pediatric Nursing Certification Board
- Chlamydia pneumoniae, generally Cpn or CpN
- Clube de Propaganda da Natação
- Coloured petri net
- Commercial Property News
- Communist Party of Nepal
- Communist Party of the Netherlands
- Community practice nurse
- Community Psychiatric Nurse
- Confederation of the Polish Nobility
- Cornish Nationalist Party
- Convertible Promissory Note
- Country and Progressive National Party, early 20th-century political party in Queensland, Australia
- Credit profile number, a credit scam using stolen Social Security numbers
- Custom part number
- Customer Premises Network