COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“Young children constantly invent new explanations to account for complex processes. And since their inventions change from week to week, furnishing the “correct” explanation is not quite so important as conveying a willingness to discuss the subject. Become an “askable parent.””
—Ruth Formanek (20th century)