COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“I have met charming people, lots who would be charming if they hadn’t got a complex about the British and everyone has pleasant and cheerful manners and I like most of the American voices. On the other hand I don’t believe they have any God and their hats are frightful. On balance I prefer the Arabs.”
—Freya Stark (1893–1993)