COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“By “object” is meant some element in the complex whole that is defined in abstraction from the whole of which it is a distinction.”
—John Dewey (1859–1952)