COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“Uneducated people are unfortunate in that they do grasp complex issues, educated people, on the other hand, often do not understand simplicity, which is a far greater misfortune.”
—Franz Grillparzer (1791–1872)