COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“We must open our eyes and see that modern civilization has become so complex and the lives of civilized men so interwoven with the lives of other men in other countries as to make it impossible to be in this world and out of it.”
—Franklin D. Roosevelt (1882–1945)