COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Famous quotes containing the word complex:
“In ordinary speech the words perception and sensation tend to be used interchangeably, but the psychologist distinguishes. Sensations are the items of consciousness—a color, a weight, a texture—that we tend to think of as simple and single. Perceptions are complex affairs that embrace sensation together with other, associated or revived contents of the mind, including emotions.”
—Jacques Barzun (b. 1907)