Conditioned Place Preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. This paradigm can also be used to measure conditioned place aversion with an identical procedure involving aversive stimuli instead. Both procedures usually involve mice or rats as subjects. This procedure can be used to measure extinction and reinstatement of the conditioned stimulus. Certain drugs are used in this paradigm to measure their reinforcing properties. Two different methods are used to choose the compartments to be conditioned, and these are biased vs. unbiased. The biased method allows the animal to explore the apparatus, and the compartment they least prefer is the one that the drug is administered in and the one they most prefer is the one where the vehicle is injected. This method allows the animal to choose the compartment they get the drug and vehicle in. In comparison, the unbiased method doesn't allow the animal to choose what compartment they get the drug and vehicle in and instead the researcher chooses the compartments.
Read more about Conditioned Place Preference: Conditioning Procedure, Knockout Mice, See Also
Famous quotes containing the words conditioned, place and/or preference:
“Women born at the turn of the century have been conditioned not to speak openly of their wedding nights. Of other nights in bed with other men they speak not at all. Today a woman having bedded with a great general feels free to tell us that in bed the general could not present arms. Women of my generation would have spared the great general the revelation of this failure.”
—Jessamyn West (1907–1984)
“See, there is a place by me where you shall stand on the rock; and while my glory passes by I will put you in a cleft of the rock, and I will cover you with my hand until I have passed by;
then I will take away my hand, and you shall see my back; but my face shall not be seen.””
—Bible: Hebrew, Exodus 33:21-23.
“It is impossible for us to love anything without some respect to ourselves; and we only consult our own inclination and our own pleasure when we prefer our friends to ourselves. And yet this preference is the only thing that can render friendship perfect and sincere.”
—François, Duc De La Rochefoucauld (1613–1680)