Limitations
CMA does not solve meta-analysis's problem of "garbage in, garbage out." However, when a class of studies is deemed garbage by a critic, it does offer a way of examining the extent to which those studies may have changed a result. Similarly, it offers no direct solution to the problem of which method to choose for combination or weighting. What it does offer, as noted above, is triangulation, where agreements between methods may be obtained, and disagreements between methods understood across the range of possible combinations of studies.
Read more about this topic: Combinatorial Meta-analysis
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