Computing
- COM (hardware interface) (or COM:), a serial port interface on IBM PC-compatible computers
- .com, an Internet top-level domain, originally short for "commercial"
- COM file, or .com file, short for "command", a file extension for an executable file in MS-DOS
- Component Object Model, a Microsoft software interface technology
- Computer
- Computer-on-module, a type of single-board computer
- Computer Output Microfilm
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