Other Uses
- Columbus (ISS module), the European module for the International Space Station
- Columbus (spacecraft), a program to develop a European space station 1986-1991
- Columbus (novel), a 1941 novel by the British writer Rafael Sabatini depicting the explorations of Christopher Columbus
- Columbus (song), a song by the band Kent from their album Tillbaka till samtiden
- COLUMBUS, ab initio quantum chemistry software
- ColumBus, former name of Howard Transit in Howard County, Maryland
- Carry On Columbus, a 1992 film
- Knights of Columbus, fraternal organization of Roman Catholic men
- MS Columbus, a cruise ship owned by Hapag-Lloyd
- SS Columbus (1873), an American merchantman converted in 1878 into the Russian cruiser Asia
- SS Columbus (1924), a transatlantic ocean liner for the North German Lloyd steamship line
- SS Christopher Columbus, Great Lakes excursion liner (1893 - 1933)
- SS City of Columbus, a passenger steamer that sailed from Boston to Savannah and sank off Martha's Vineyard
- USS Columbus, various ships of the US Navy
- Columbus Tubing, an Italian manufacturer of bicycle frame tubing
- Columbus Salame, an American food processing company
- Columbus (Star Trek), a shuttlecraft in Star Trek series
- Columbus hops, a variety of hops
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