Collaborative Studies On Genetics of Alcoholism - Brain Wave

Brain Wave

The brain wave is called an event-related potential (ERP) and is similar to an EEG. Brainwaves are monitored in a non-invasive procedure that involves placing a cap on the subject's head, similar to a bathing cap. This cap will monitor the brain's natural electrical activity and will record the brain's response when the subject is presented with various stimuli. Subjects respond to computer programs on a screen in front of them that flash various stimuli on the screen.

After a significant event, or an important stimuli to which the subject is instructed to respond, there is an increase in electrical activity. COGA is investigating, for example, the P3 (or P300) peak of the ERP that occurs approximately 300 ms after the stimuli presentation. Varying amplitudes of the wave have different behavioral implications. The amplitude is fairly consistent throughout families and steady across time, suggesting an inherited component, as opposed to an environmental component.

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