CNE may refer to:
- Cairde na hÉireann, (Friends of Ireland) The National Structure for Republicans in Scotland
- Canadian National Exhibition, in Toronto, Ontario
- Cernavodă Nuclear Power Plant
- Central New England Railway
- Certified Novell Engineer, advancing from Certified Novell Administrator
- Contrat nouvelle embauche a French employment contract
- Centre for the New Europe
- Comissão Nacional de Eleições (National Election Commission of Portugal)
- Corpo Nacional de Escutas – Escutismo Católico Português (Portugal Catholic Scouts Association)
- National Electoral Council (Colombia) (Spanish: Consejo Nacional Electoral)
- National Electoral Council (Venezuela) (Spanish: Consejo Nacional Electoral)
- National Emergency Commission of Costa Rica
- Computer Network Exploitation, a variant of Computer network operations, Cyber Operations, and Network-centric warfare