Adverse Effects
This drug may cause lightheadedness, dry mouth, dizziness and constipation. Clonidine may also cause hypotension.
Clonidine also has peripheral alpha agonist activity which can lead to hypertension - especially when it is injected intravenously. This blood pressure increase is sometimes witnessed in cases of overdose in children. As the clonidine is eliminated by the body, the peripheral effects wear off and its basic hypotensive effect becomes evident. Both the hypertensive and hypotensive effects can be harmful.
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