Investigation and Findings
The scientific work of Dr. Picado was prolific and very extensive; it is calculated that he wrote about 115 research papers in his lifetime, delving into nearly all aspects of his environment: soil, flora, fauna, human tissues,water, and others. Among them are included books and monographs. His work covered topics of zoology, botany of bromeliads, ophidism, physiology, phytopathology, industrial microbiology, medical microbiology, and immunology.
In March 2000, doctors from the San Juan de Dios Hospital in San José, the capital of Costa Rica, published his manuscripts, in which he explains his experiences between 1915 and 1927 with the inhibiting action of fungi of the "Penicillin sp" genre in the growth of staphylococci and streptococci (bacteria that cause a series of infections). In 1927, he demonstrated the inhibitory action of the bacillus genus penicillium sp on the proliferation of the bacteria staphylococcus and streptococcus. Although, the discovery of penicillin has been attributed to Alexander Fleming, Picados' old laboratory notebooks from 1923 show records of the antibiosis of penicillium sp.
For this reason he is renowned as one of the precursors of the penicillin antibiotic, discovered by the Scottish biologist and pharmacologist, Alexander Fleming, in 1928. The report with the results of the treatments performed with penicillin by Dr. Picado were published by the Biology Society of Paris in 1927.
Read more about this topic: Clodomiro Picado Twight
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